Subharmonic behavior of phospholipid-coated ultrasound contrast agent microbubbles
نویسندگان
چکیده
منابع مشابه
Subharmonic behavior of phospholipid-coated ultrasound contrast agent microbubbles.
Coated microbubbles, unlike tissue are able to scatter sound subharmonically. Therefore, the subharmonic behavior of coated microbubbles can be used to enhance the contrast in ultrasound contrast imaging. Theoretically, a threshold amplitude of the driving pressure can be calculated above which subharmonic oscillations of microbubbles are initiated. Interestingly, earlier experimental studies o...
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ULTRASOUND-INDUCED COALESCENCE OF CONTRAST AGENT MICROBUBBLES M. POSTEMA*1,2, C. T. LANCÉE1, N. DE JONG1,3, P. MARMOTTANT3, and S. HILGENFELDT3, 1Dept. of Experimental Echocardiography, Thoraxcentre, Erasmus MC, 2Interuniversity Cardiology Institute of The Netherlands, 3Physics of Fluids, Dept. of Applied Physics, Faculty of Science and Technology, University of Twente. Corresponding e-mail: po...
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The focus of contrast-enhanced ultrasound research has developed beyond visualizing the blood pool and its flow to new areas such as perfusion imaging, drug and gene therapy, and targeted imaging. In this work comparison between the application of polymer- and phospholipid-shelled ultrasound contrast agents (UCAs) for characterization of the capillary microcirculation is reported. All experimen...
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Previous optical studies have shown threshold behavior of single-contrast agent microbubbles. Below the acoustic pressure threshold, phospholipid-coated microbubbles with sizes <5.0 mum in diameter oscillate significantly less than above the threshold pressure. Previous studies also revealed an acoustic pressure-dependent attenuation of ultrasound by microbubble contrast agents. In this study, ...
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This work presents experimental responses of single ultrasound contrast agents to short, large amplitude pulses, characterized using double passive cavitation detection. In this technique, two matched, focused receive transducers were aligned orthogonally to capture the acoustic response of a microbubble from within the overlapping confocal region. The microbubbles were categorized according to...
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ژورنال
عنوان ژورنال: The Journal of the Acoustical Society of America
سال: 2010
ISSN: 0001-4966
DOI: 10.1121/1.3493443